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Ludwig Center for Metastasis


Feature storyThe deadliest aspect of cancer is its ability to metastasize, or migrate from one part of the body to another, where cancerous cells use a new substrate to ultimately grow into detectable and deadly tumors. While current cancer research efforts have expanded exponentially in recent years, the focus of these efforts has been on primary cancers. Metastasis as a distinct physiological process with its own dynamics has remained largely unexplored and thus poorly understood.

To help address this, the Ludwig Institute for Cancer Research has created a new Ludwig Center for Metastasis Research at the University of Chicago. Initial funding for the Ludwig Center will come from the Virginia and D.K. Ludwig Fund and consists of $6 million over 3 years, followed by an additional $12 to 14 million over a subsequent 7 years.

Co-Directing the new center are Geoffrey Greene, Ph.D., Virginia and D. K. Ludwig Professor, Ben May Institute for Cancer Research, and Ralph Weichselbaum, M.D., Daniel K. Ludwig Professor and Chairman, Department of Radiation & Cellular Oncology. The Metastasis Center will be organically linked to the reorganized and revitalized University of Chicago Cancer Research Center, which is directed by Michelle Le Beau, Ph.D.

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The Ludwig Center will ultimately be housed in the new Gwen and Jules Knapp Center for Biomedical Discovery upon its completion in early 2008. Funding from the Ludwig Trust will enable leaders at Chicago to eventually recruit a new Director and additional faculty. The first junior faculty member has already been recruited to the Division using Ludwig funds. Andy Minn, M.D., Ph.D., was recruited from Memorial Sloan-Kettering, where he recently completed a postdoctoral fellowship in Joan Massagué's laboratory. Dr. Minn earned his degrees through the Medical Scientist Training Program (MSTP) and did his graduate thesis work in Craig Thompson's laboratory through the Committee on Immunology. Ludwig funds will also be used to support pilot funding in metastasis research and core technology.

 

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